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 Part Two - Cells and Energy 67

 7. Pathways that harvest Chemical Energy 138

7.1 How Does Glucose Oxidation Release Chemical Energy? 139
Cells trap free energy while metabolizing glucose 139
An overview: Harvesting energy from glucose 140
Redox reactions transfer electrons and energy 140
The coenzyme NAD is a key electron carrier in redox reactions 141

7.2 What Are the Aerobic Pathways of Glucose Metabolism? 142
The energy-investing reactions of glycolysis require ATP 142
The energy-harvesting reactions of glycolysis yield NADH + H+ and ATP 144
Pyruvate oxidation links glycolysis and the citric acid cycle 144
The citric acid cycle completes the oxidation of glucose to CO2 145
The citric acid cycle is regulated by concentrations of starting materials 147

7.3 How Is Energy Harvested from Glucose in the Absence of Oxygen? 147

7.4 How Does the Oxidation of Glucose Form ATP? 148
The electron transport chain shuttles electrons and releases energy 149
Proton diffusion is coupled to ATP synthesis 150

7.5 Why Does Cellular Respiration Yield So Much More Energy Than Fermentation? 153

7.6 How Are Metabolic Pathways Interrelated and Controlled? 154

Catabolism and anabolism involve interconversions of biological monomers 154
Catabolism and anabolism are integrated 155
Metabolic pathways are regulated systems 155

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