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 Part Five -The Patterns and Processes of Evolution 463

 24. The Evolution of Genes and Genomes 524

24.1 What Can Genomes Reveal about Evolution? 525
Evolution of genomes results in biological diversity 525
Genes and proteins are compared through sequence alignment 526
Models of sequence evolution are used to calculate evolutionary divergence 527
Experimental studies examine molecular evolution directly 527

24.2 What Are the Mechanisms of Molecular Evolution? 530
Much of evolution is neutral 531
Positive and stabilizing selection can be detected in the genome 532
Genome size and organization also evolve 533
New functions can arise by gene duplication 534
Some gene families evolve through concerted evolution 535

24.3 What Are Some Applications of Molecular Evolution? 536
Molecular sequence data are used to determine the evolutionary history of genes 537
Gene evolution is used to study protein function 538
In vitro evolution produces new molecules 538
Molecular evolution is used to study and combat diseases 538

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