11.1
What Is the Evidence that the Gene
is DNA? 233
DNA from one type of bacterium genetically
transforms another type 233
The transforming principle is DNA
234
Viral replication experiments confirmed
that DNA is the genetic material 235
Eukaryotic cells can also be genetically
transformed by DNA 237
11.2
What Is the Structure of DNA? 23
The chemical composition of DNA was
known 238
Watson and Crick described the double
helix 238
Four key features define DNA structure
239
The double-helical structure of DNA
is essential to its function 241
11.3 How
Is DNA Replicated? 241
Three modes of DNA replication appeared
possible 241
Meselson and Stahl demonstrated that
DNA replication is semiconservative
241
There are two steps in DNA replication
242
DNA is threaded through a replication
complex 243
DNA polymerases add nucleotides to
the growing chain 245
Telomeres are not fully replicated
247
11.4
How Are Errors in DNA Repaired? 249
11.5 What
Are Some Applications of Our Knowledge
of DNA Structure and Replication?
250
The polymerase chain reaction makes
multiple copies of DNA 250
The nucleotide sequence of DNA can
be determined 251