CHIME proteins

• HIV-1 reverse transcriptase, 1HMV.pdb and 1RT1.pdb
• reverse transcriptase/RNA complex, 1HVU.pdb
• reverse transcriptase/DNA complex, 1RTD.pdb
• gp 120 (glycoprotein 120) complexed with IgG, 1GG1.pdb
• gp 41 (glycoprotein 41) core fragment 1AIK.pdb
• gp 41, spliced fragment (amino acids 1-34 and 41-68), 1DF4.pdb
• gag protein, with zinc, 2ZNF.pdb
• gag protein, fragment, 1FGL.pdb
• HIV nucleocapsid 1AAF.pdb

Web Links

• PDB search site
• All the Virology on the WWW
• Society for General Microbiology (Download Article on Retrovirus Mutation Rates)
• Universal Virus Database
• HIV Sequence Database
• National Human Genome Research Institute, Glossary of Genetic Terms
• Microbiology and virology resources
• Cold Spring Harbor, DNA from the Beginning

Further Reading

1. AIDS and other Immunodeficiencies (Chapter 19) in R. A. Goldsby, T. J. Kindt, and B. A. Osborne. Kuby Immunology, 4th edition, W. H. Freeman and Co., pp. 467-496, 2000.
2. H. Lodish, A. Berk, S. L. Zipursky. P. Matzudaira, D. Baltimore and J. Darnell. Molecular Cell Biology, 4th edition, W. H. Freeman and Co., pp. 200-203, 409, 1065-1066, 1999.
3. B. Purves, G. Orians, C. Heller and D. Sadava. Life - The Science of Biology,  5th edition, Sinauer and W. H. Freeman and Co., pp. 264-265, 282-304, 424-426, 1998.
4. L. Stryer. Biochemistry,4th edition, W. H. Freeman and Co. pp. 58, 91, 229-230, 384-386, 1995.
5. R. C. Gallo.  Human retroviruses in the second decade: a personal perspective.  Nature Medicine 1:753-759, 1995.
6. E. Meinl , H. Fickenscher, M. Thome, J. Tschopp and B. Fleckenstein.  Anti-apoptotic strategies of lymphotropic viruses.  Immunology Today 19:474-470, 1998.
7. M. Salemi, A. M. Vandamme, J. Desmyter, C. Casoli and U. Bertazzoni.  The origin and evolution of human T-cell lymphotropic virus type II (HTLV-II) and the relationship with its replication strategy.  Gene 234:11-21, 1999.
8. R. A. Weiss,  D. Griffiths, Y. Takeuchi, C. Patience and P. J. Venables.  Retroviruses: ancient and modern.  Archives of Virology (Supplement) 15:171-177, 1999.

Acknowledgements

Derived from H. Lodish, et al., Molecular Cell Biology text and CD-ROM, 4th edition, © 2000 W. H. Freeman and Co. and Sumanas, Inc.

Virginia Scofield, University of Southern California, Los Angeles, CA.