Fully Updated Coverage of Recent Developments
The new edition takes into account recent discoveries that have changed how scientists think about the fundamental concepts in biochemistry and human health. Particular attention has been paid to the following topics:
• The metabolic basis of cancer and the role of glycolysis in cancer
(Chapters 16 and 18)
• The biochemical roles of glycoproteins (Chapter 10)
• Recombination in DNA repair (Chapter 35)
• Quantitative PCR (Chapter 41)
Expanded Coverage of Experimental Techniques
Chapter 5, Techniques in Protein Biochemistry, and Chapter 41, Immunological and Recombinant DNA Techniques, explore important techniques used by biochemists in the past as well as new technologies with which biochemists make discoveries in present-day laboratories.
Metabolism in Context: Diet and Obesity
The new Metabolism in Context sections show how new information on the role of leptins in hunger and satiety has changed the way biochemists think about obesity and diabetes. In addition to diet and obesity, other Metabolism in Context features focus on metabolism and cancer, and metabolism and exercise.
Biochemistry in Context
• Clinical Insights show how our understanding of biochemical concepts influences an aspect of a disease or its cure.
• Biological Insights show how simple changes in biochemical processes can have dramatic effects.
• Nutrition Examples explore the underlying relationship between nutrition and biochemistry
• Vitamin and Coenyzme Appendix provides information on nine key vitamins, including food sources and consequences of deficiencies, plus page references to discussions of each in the text.
50% More End-of-Chapter Problems
• New Challenge Problems require calculations, understanding of chemical structures, and other concepts that are challenging for most students.
• Data Interpretation Problems train students to analyze data and reach scientific conclusions.
• Chapter Integration Problems connect concepts across chapters.
• Many end-of-chapter problems are now clearly linked to the Learning Objectives set at the beginning of each chapter.